Neutrophil and monocyte kinetics in a case of cyclic neutropenia.

The kinetics of neutrophilic granulocytes half disappearance time shortened to 2.3 hr. and monocytes were examined simulMoreover, the intravascular granulocyte dietaneously in a patient suffering from cyclic tribution changed in favor of the marginal neutropenia. During the remission phase of granulocyte pool. During the neutropenic the disease the observed kinetic data for phase, the intravascular monocyte pools both cell types did not deviate significantly were Increased and monocyte half-disapfrom the normal range. At a stage just pearance time was prolonged to 1 4 hr; the before the minimal blood granulocyte count monocyte turnover rate was 2.4-fold higher was reached, the total blood granulocyte than during remission. pool was diminished and the granulocyte